My entire family has a complete inability to turn on the TV downstairs. The concept of 3 remote controls is beyond their collective grasp (1 for the TV, 1 for the sound system and 1 for the decoder box).
This problem reached an all-time low this morning when my sister, who was coming out to us for dinner, phoned ahead to get me to turn on the TV for her before i left.
Coincidentally, i also found the best solution ever to this problem today on a design blog.
I made my own versions of these. 1 of the remotes now only allows access to the power button. The other one allows access only to volume controls.